Griseofulvin BP 125mg

Griseofulvin BP 125mg


Griseofulvin is an antifungal antibiotic. It inhibits cell division and DNA production of the fungi. It is active against the common dermatophytes, including some species of Epidermophyton, Microsporum, or Trichophyton.

Indications
Griseofulvin is used in the treatment of infections of the scalp, hair, nails, and skin that does not respond to topical treatment.
Griseofulvin may also be beneficial in treating infections in the soles of the feet, palms of the hands, and nails.

Composition
Each tablet contains Griseofulvin 125mg

Dosage
The usual dosage for adults is 500mg to 1g daily in single or divided doses Children may be given 10mg per kg body-weight daily. The duration of treatment could be 2 to 6 weeks for infections of the hair and skin, up to 6 months for infections of the fingernails, and 12 months or more for infections of the toenails. Griseofulvin is best given with or after meals.

Contraindications
Griseofulvin is contraindicated in patients with severe liver disease or systemic lupus erythematosus (a systemic disease whereby the body's immune system attacks the body's own cells). Griseofulvin is also contraindicated in pregnancy. Women should not become pregnant during or within 1 month of stopping Griseofulvin treatment. For similar reasons, men receiving Griseofulvin should not father children within 6 months of treatment.

 

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