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Chlorpheniramine Maleate is a
sedating antihistamine. Chlorpheniramine maleate is used for the
symptomatic relief of allergic conditions including urticaria,
rhinitis, watery and itchy eyes, coughs, colds, and in pruritic
skin disorders.
Composition
Chlorpheniramine Maleate BP 4mg
Dosage
Adults: Chlorpheniramine maleate
tablets are given by mouth in doses of 4mg every 4 to 6 hours
(maximum 24mg daily)
Children: 1 to 2 years, 1mg two
times daily; 2 to 5 years, 1mg every 4 to 6 hours (maximum 6mg
daily) 6 to 12 years, 2mg every 4 to 6 hours (maximum 12mg
daily).
Contraindications
Should not be used in patients with conditions such as
angle-closure glaucoma, urinary retention, prostatic
hyperplasia, or pyloroduodenal obstruction. Should not be given
to children below 2 years.
Warnings and Precautions
The maximum recommended dose should not be exceeded. Drowsiness
may occur and persist for hours. Patients must not drive or operate machinery when taking Chlorpheniramine maleate tablets.
Should not be taken with alcohol or other drugs with respiratory depressant effects.
Side Effects
It May cause drowsiness, lassitude, dizziness and incoordination,
dry mouth, constipation, and gastric reflux.
Drug Interactions
Chlorpheniramine Maleate tablets may interact with barbiturates,
hypnotics, opiod analgesics, anxiolytic sedatives,
antipsychotics, antimuscarinic drugs, such as atropine and some
antidepressants.
Overdose
Overdosage may result in excitement, tremors, psychoses, raised
body temperature, hallucinations and convulsions. Coma and
cardio-respiratory collapse may follow. Symptomatic management
of the anti-muscarinic effects is recommended.
Storage
The tablets should be stored below 30⁰C and away from moisture and light. |
